Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
651166 is a mixture of monoclonal antibodies that target p0071 Multiepitope.
Detects a plaque protein (p0071) specific for a subtype of adherens junctions, with a molecular mass of 135 kD and is closely related to neurojungin/delta-catenin and ARVC (all belonging to the p120 armadillo subfamily). p0071 is specifically detected in the plaques of the composite junctions (area compositae) of cardiac intercalated disks, in puncta adhaerentia of single- and multi-layered epithelia and blood vessel endothelial cells.; it is, however, absent from desmosomes. This protein was also described as plakophilin 4.Reactivity on cultured cell lines: MCF-7, A431, CaCo-2, HT-29, PLC, 16HBE14o, HaCaT, SV80, U333 CG, 3T3, RVF-SMC, MH1C1.Positive control: MCF-7 cells.
Plays a role as a regulator of Rho activity during cytokinesis. May play a role in junctional plaques.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Armadillo-related protein; catenin 4; p0071; Plakophilin-4
Gene Aliases: 5031422I09Rik; 9430019K17Rik; Armrp; p0071; PKP4
UniProt ID: (Human) Q99569, (Mouse) Q68FH0
Entrez Gene ID: (Human) 8502, (Bovine) 281406, (Mouse) 227937
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn moreGet expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support