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Invitrogen
p41-ARCb Polyclonal Antibody
Advanced Verification
This Antibody was verified by Relative expression to ensure that the antibody binds to the antigen stated.
Product Details
PA5-52119
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human p41-ARCb. Recombinant protein control fragment (Product #RP-102409).
Conjugate
Form
Liquid
Concentration
0.1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_2645145
Product Specific Information
Immunogen sequence: TVCLADADKK MAVATLASET LPLLALTFIT DNSLVAAGHD CFPVLFTYDA AAGMLSFGGR LDVPKQSSQR GLTARERFQN LDKKASSEGG TAAGAGLDSL HKNSVSQISV LSGGKAKCSQ FCTTGMDGGM SIWDVKSLES A
Highest antigen sequence identity to the following orthologs: Mouse - 94%, Rat - 94%.
Target Information
This gene encodes one of seven subunits of the human Arp2/3 protein complex. This subunit is a member of the SOP2 family of proteins and is most similar to the protein encoded by gene ARPC1A. The similarity between these two proteins suggests that they both may function as p41 subunit of the human Arp2/3 complex that has been implicated in the control of actin polymerization in cells. It is possible that the p41 subunit is involved in assembling and maintaining the structure of the Arp2/3 complex. Multiple versions of the p41 subunit may adapt the functions of the complex to different cell types or developmental stages. This protein also has a role in centrosomal homeostasis by being an activator and substrate of the Aurora A kinase.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: actin related protein 2/3 complex subunit 1B, 41kDa; actin related protein 2/3 complex, subunit 1B, 41kDa; Actin-related protein 2/3 complex subunit 1B; Actin-related protein complex 1b; Arp2/3 complex 41 kDa subunit; ARP2/3 protein complex subunit p41; OTTHUMP00000206020; p41-ARC
Gene Aliases: 41kDa; AA408064; AA408534; AA571392; AF007010; ARC41; ARPC1B; AW208418; L72; p40-ARC; p41-ARC; SOP2Hs
UniProt ID: (Human) O15143, (Rat) O88656, (Mouse) Q9WV32
Entrez Gene ID: (Human) 10095, (Rat) 54227, (Mouse) 11867
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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