Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
FIGURE: 1 / 1
Polycomb group (PcG) protein that binds to the 5'-CNGCCATNNNNG-3' sequence found in the regulatory regions of many genes. PcG proteins act by forming multiprotein complexes, which are required to maintain the transcriptionally repressive state of homeotic genes throughout development. PcG proteins are not required to initiate repression, but to maintain it during later stages of development. They probably act via the methylation of histones, rendering chromatin heritably changed in its expressibility. Probably targets the Esc/E(z) complex to DNA. Necessary but not sufficient to recruit a functional PcG repressive complex that represses target genes, suggesting that the recruitment of the distinct PRC1 complex is also required to allow a subsequent repression.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: CG17743-PA; CG17743-PB; peiohomeotic; PHO; pho-PA; pho-PB; pleihomeotic; pleohomeotic; Polycomb protein PHO; Polycomb protein PHO pho CG17743; polyhomeotic; Protein pleiohomeotic; RE17954p; Transcription factor YY1 homolog; zinc finger protein
Gene Aliases: CG17743; Dmel\CG17743; Dmel_CG17743; dYY1; l(4)102EFc; l(4)29; l(4)BU-2; l(4)OC-1; l(4)pho; PHO; PHO/YY1; YY1
UniProt ID: (Fruit fly) Q8ST83
Entrez Gene ID: (Fruit fly) 43819
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn moreGet expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support