Cryo-Electron Tomography

Cryo-electron tomography: structural biology on a proteomic scale

The interior of cells can be mysterious. Join other scientists as they access the inner workings of cells in 3D and at unprecedented nanoscale resolution using cryo-electron tomography (cryo-ET). Here at Thermo Fisher Scientific we are continuing to innovate to increased automation for focused ion beam milling of cell and tissues samples, providing higher throughput data and ease-of-use for tomography data acquisition, as well as faster and more advanced imaging processing workflows. 

Molecular architecture revealed

Cryo-electron tomography overview

How does cryo-electron tomography work?

Discover cryo-electron tomography which delivers both structural informational about individual proteins as well as their spatial arrangement within the cell.

<h2>Cryo electron tomography tilt series</h2>

Cryo-electron tomography of cells

Cryo-ET explores the ultrastructure of cells in nanometer resolution. See the data that has been obtained using this technique. 

Cryo electron tomography imaging of endoplasmic reticulum membrane.

Cryo-electron tomography webinar library

Watch our latest webinars with leading scientists using cryo-ET to advance their research. 

Webinar cover for understanding cellular structure with cryo ET

Cryo-electron tomography eBook

Explore how cryo-ET is making scientific advances in various fields like cell biology, neuroscience, microbiology, and virology with this curated collection.

Cryo tomography publication eBook cover

Cryo-ET sample preparation and data analysis support

We offer integrated solutions to support you from sample preparation to data analysis.

Cell culture preparation for cryo ET

Cryo-ET lab support and training

Whether you are integrating a new cryo-FIB to your cryo-TEM or implementing an entire workflow, our team of experts will set you up for success.

Cryo ET data acquisition

For Research Use Only. Not for use in diagnostic procedures.

1x1 image pixel for data collection