Preimplantation Research Testing | Thermo Fisher Scientific

Research testing solutions

What is preimplantation genetic testing (PGT)?

Preimplantation genetic testing is a rapidly growing area of fertility research commonly incorporated into IVF research workflows. PGT findings can determine chromosome presence and frequency in embryo biopsies, which provides scientific insight into reducing the time to pregnancy and decreasing miscarriage rates.

Two types of testing solutions are commonly used in PGT to evaluate the status of an embryo.

Preimplantation genetic testing-aneuploidy (PGT-A)

Used for detection of aneuploidies, or chromosomal abnormalities, across all 24 chromosomes (22 autosomes and the X and Y chromosomes)
Examples include trisomy 21 (Down syndrome) and monosomy X (Turner syndrome)

Preimplantation genetic testing-monogenic (PGT-M)

Linkage analysis identifies relevant alleles for single gene disorders
Examples include sickle cell anemia, cystic fibrosis, Huntington disease, fragile-X, and spinal muscular dystrophy

Hear from experts and learn about PGT

On-demand symposium: Innovation and trends in reproductive health genetic testing

This session, from ESHRE 2024, covers advanced topics such as delivering premium preimplantation genetic testing (PGT) add‑ons to enhance traditional PGT, demystifying PGT‑A with a focus on invasive vs non‑invasive PGT‑A approaches, and exploring the implications of coelocentesis on fetal health, particularly in detecting chromosome aneuploidies and monogenic disorders.

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On-demand roundtable: Demystifying preimplantation genetic testing for monogenic disorders (PGT-M) in the public sector

In this roundtable, we focus on PGT for monogenic disorders (PGT-M) specifically within the public sector, analysing the presence of genetic mutations in single gene linked disorders.

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On-demand roundtable: non-invasive vs invasive PGT

In this on-demand roundtable, we are exploring the particulars of non-invasive and invasive PGT and experts in the field are sharing their insights on the advantages, challenges, and the evolving landscape of genetic testing.

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On-demand talk: Simplified PGT workflow on a single embryo biopsy

In this talk you will gain an understanding on how to integrate a workflow for both PGT-A and PGT-M on NGS from a single embryo biopsy. Additionally, you will learn about our premium PGT-A analysis with SNP-based quality controls. Explore how SNPs can offer genetic insights on polyploidy, maternal contamination, and sibling identity.

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