HPLC

Columns are the heart of chromatography. We recommend having robust go-to reverse phase columns. Most chromatographers would say that the majority of separations can be accomplished by a C18 column. For situations where you are working with more challenging separations, we also provide a few additional options below.

Learn more about our HPLC resources and portfolio

  • Accucore Vanquish C18 columns are high resolution columns that take full advantage of the separation power provided by Vanquish Horizon systems. These columns are on a robust solid core silica particle, and deliver powerful separations to solve your analytical challenges faster and more effectively.
  • Accucore Phenyl Hexyl columns are HPLC/UHPLC solid core columns for the separation of positional isomers. This aromatic chemistry offers complementary selectivity to C18 phases, and is a great option for clinical research, forensic toxicology, and pharmaceutical laboratories.
  • Accucore aQ columns are HPLC/UHPLC solid core columns for high resolution, low back pressure separations, fully end-capped and compatible with 100% aqueous mobile phases.
  • Hypersil Gold columns offer our most popular chemistry in a HPLC and UHPLC format. They can be used for the separation of a wide variety of analytes and are a go-to for customers in pharmaceutical, food and beverage, clinical research, and environmental labs. Responds well and with high efficiency peaks in a wide variety of matrices.
  • Accucore RP-MS columns offers our Hypersil GOLD chemistry on a solid core format. This column is optimized for MS detection and offers excellent peak shapes for optimal separations.

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Ordering information

LC columns

Catalog # Name Price (USD) Qty
27101-102130 Accucore™ Vanquish™ C18+ Reversed Phase HPLC Column, 1.5 μm, 2.1 mm x 100 mm
897.18

Special offer

Online exclusive

Ends: 30-Jun-2025

1,281.24
Save 384.06 (30%)
27101-052130 Accucore™ Vanquish™ C18+ Reversed Phase HPLC Column, 1.5 μm, 2.1 mm x 50 mm
765.05

Special offer

Online exclusive

Ends: 30-Jun-2025

1,092.55
Save 327.50 (30%)
17926-052130 Accucore™ Phenyl/Hexyl Reversed Phase HPLC Column, 2.6 μm, 2.1 mm x 50 mm
548.78

Special offer

Online exclusive

Ends: 30-Jun-2025

783.70
Save 234.92 (30%)
17326-102130 Accucore™ aQ C18 Reversed Phase HPLC Column, 2.6 μm, 2.1 mm x 100 mm, Each
644.84

Special offer

Online exclusive

Ends: 30-Jun-2025

920.88
Save 276.04 (30%)
25002-102130 Hypersil GOLD™ C18 Selectivity Reversed Phase HPLC Column, 1.9 μm, 2.1 mm x 100 mm, Each
715.34

Special offer

Online exclusive

Ends: 30-Jun-2025

1,021.56
Save 306.22 (30%)
25003-102130 Hypersil GOLD™ C18 Selectivity Reversed Phase HPLC Column, 3 μm, 2.1 mm x 100 mm, Each
707.27

Special offer

Online exclusive

Ends: 30-Jun-2025

1,010.03
Save 302.76 (30%)
17626-102130 Accucore™ RP-MS Proprietary Reversed Phase HPLC Column, 2.6 μm, 2.1 mm x 100 mm, Each
644.84

Special offer

Online exclusive

Ends: 30-Jun-2025

920.88
Save 276.04 (30%)

Filters

Basic filters are also a necessity to prevent clogging of your column. Here are some that we recommend to get you up and running.

Sample handling