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Human CFHR1 quantitates human CFHR1 in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant human CFHR1.
This gene encodes a secreted protein belonging to the complement factor H protein family. It binds to Pseudomonas aeruginosa elongation factor Tuf together with plasminogen, which is proteolytically activated. It is proposed that Tuf acts as a virulence factor by acquiring host proteins to the pathogen surface, controlling complement, and facilitating tissue invasion. Mutations in this gene are associated with an increased risk of atypical hemolytic-uremic syndrome.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Gene aliases : CFHL, CFHL1, CFHL1P, CFHR1, CFHR1P, FHR1, H36-1, H36-2, HFL1, HFL2
Gene ID : (Human) 3078
Gene symbol : CFHR1
Protein Aliases : complement factor H-related 1 pseudogene, Complement factor H-related protein 1, FHL-1, FHR-1, H factor (complement)-like 1, H factor (complement)-like 2, H factor-like protein 1, H-factor-like 1, H36
UniProt ID (Human) Q03591
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