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Search Thermo Fisher Scientific
Invitrogen
Human TIMP-3 quantitates human TIMP-3 in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant human TIMP-3.
Tissue inhibitor of metalloproteinase 3 (TIMP3) is a member of the tissue inhibitor of metalloproteinases gene family. It functions to inhibit the activity of matrix metalloproteinases (MMP) which degrade components of the extracellular matrix. TIMP3 is expressed upon mitogenic stimulation. It binds irreversibly to zinc-dependent MMPs and inactivates them by binding to their catalytic zinc cofactor. Other functions of TIMP3 include nervous system development, tissue regeneration, and visual perception. In humans, the gene encoding TIMP3 is located on chromosome 22.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Gene aliases : HSMRK222, K222, K222TA2, SFD, TIMP3
Gene ID : (Human) 7078
Gene symbol : TIMP3
Protein Aliases : Metalloproteinase inhibitor 3, MIG-5 protein, Protein MIG-5, TIMP 3, TIMP-3, Tissue inhibitor of metalloproteinases 3
UniProt ID (Human) P35625
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