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Murine IL-5 ELISA development kit contains the key components required for the quantitative measurement of natural and/or recombinant murine IL-5 in a sandwich ELISA format. Using the ELISA protocol, the recommended microplates, reagents and solutions, the components supplied in this kit are sufficient to assay murine IL-5 in approximately 200 ELISA plate wells.
This PeproTech ABTS ELISA Development Kit contains the key components required for the quantitative measurement of natural and/or recombinant proteins in a sandwich ELISA format. This ABTS ELISA Development Kit contains enough material to assay the target cytokine in at least 200 ELISA plate wells. The ABTS ELISA Buffer Kit (Product # 900-K00), sold separately, is recommended to be used in conjunction with this ABTS ELISA Development Kit for optimal performance. This buffer kit contains all the necessary components to assay ten 96-well ELISA plates (included) and contains detailed handling instructions.
IL-5 is a cytokine that acts as a growth and differentiation factor for both B cells and eosinophils. IL-5 cytokine is a main regulator of eosinopoiesis, eosinophil maturation and activation. The elevated production of this cytokine is reported to be related to asthma or hypereosinophilic syndromes. The receptor of IL-5 cytokine is a heterodimer, whose beta subunit is shared with the receptors for interleukine 3 (IL3) and colony stimulating factor 2 (CSF2/GM-CSF). IL-5, together with those for interleukin 4 (IL4), interleukin 13 (IL13), and CSF2, form a cytokine gene cluster on chromosome 5. IL-5, IL4, and IL13 are found to be regulated coordinately by long-range regulatory elements spread over 120 kilobases on chromosome 5q31.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Gene aliases : Il-5, Il5
Gene ID : (Mouse) 16191
Gene symbol : Il5
Protein Aliases : B-cell growth factor II, BCGF-II, Cytotoxic T-lymphocyte inducer, Eosinophil differentiation factor, IL-5, Interleukin-5, T-cell replacing factor, TRF
UniProt ID (Mouse) P04401
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