Copper(II) acetate monohydrate is used in formation of Cu chelates of β-dicarbonyl compounds as a means of purification and in the eglinton (modified glaser) coupling of terminal alkynes. It is also used as a catalyst for the michael reaction giving increased yields and absence of side-reactions. It Promotes ullmann-type C-O and C-N coupling reactions of arylboronic acids with phenols, amines and various other nitrogen derivatives. It is also used in biochemical applications such as DNA extraction.
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