Chlorodiphenylphosphine is used in the synthesis of various phosphines and an useful reagent in for the introduction of Ph₂P group. It is also useful as an intermediate to make antioxidants, flame retardants, stabilizers, catalysts, photoinitiators and optical brighteners. It is also used to produce diphenylphosphinous acid methyl esters. It is used as a precursor in the preparation of various phosphines. It is involved in the preparation of phosphines, which is used as stabilizers for plastics, flame retardants and UV-hardening paint systems.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.