Polyethyleneimine is used for protein and nucleic acid precipitation, transfection assays and to pretreat filters to increase the binding of proteins. It can also complex heavy metal ions. An effective permeabilizer of gram negative bacteria. Crosslinked polyethyleneimine is used as an enzyme carrier. It is used as a membrane lubricant, useful in filtering frozen cell membranes and for the separation of nucleotide mixtures. Polyethyleneimine cellulose in small columns will separate cyclic nucleotides from related compounds at the same electrolyte concentration that is used for thin layer chromatography on PEI cellulose-coated plates. It is also used in separation medium for thin layer chromatography, paper chromatography and Low pressure liquid chromatography. Polyethylenimine on silica gel is used for thin layer chromatography.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.