Decaborane is used as a fuel for aneutronic fusion. It is also used in the preparation of vinyl decaborane as well as in the preparation of semiconductors that have low energy ion implantation. It is widely used in rocket propellants and serves as a catalyst in olefin polymerization reactions. It is a reactant for the preparation of carborane-conjugated quinoline carboxamide ligands of translocator protein for boron neutron capture therapy (BNCT).

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