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Cinchonidine, 98.5-101%
Catalog number: 110331000
100 g, Each
Thermo Scientific Chemicals
Cinchonidine, 98.5-101%
Catalog number: 110331000
100 g, Each
Quantity
Chemical Identifiers
CAS
485-71-2
IUPAC Name
{5-ethenyl-1-azabicyclo[2.2.2]octan-2-yl}(quinolin-4-yl)methanol
Molecular Formula
C19H22N2O
InChI Key
KMPWYEUPVWOPIM-UHFFFAOYNA-N
SMILES
OC(C1CC2CCN1CC2C=C)C1=C2C=CC=CC2=NC=C1
Specifications
Specification SheetAppearance (Form)
Crystalline powder
Melting point
>=200°C
Titration with HClO4
98.5 to 101.0 % (On dried substance)
Specific optical rotation
-105° to -115° (20°C, 589 nm) (c=1, EtOH)
Infrared spectrum
Conforms
Description
This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
General Description
Cinchonidine is an alkaloid naturally occurring in the bark of Cinchona strubs that has activity against Plasmodium spp
Cinchonidine is a diastereoisomer of cinchonine and can be used to promote chirality in asymmetric or enantioselective synthesis of organic compounds
Applications
Cinchonidine has been used as a starting material in the synthesis of anti-malarial cinchona alkaloid conjugates
Has been shown to potently induce γ-globin mRNA and fetal hemoglobin in erythroid progenitor cells and may be useful in preclinical studies of β-thalassemia
RUO – Research Use Only
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