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            Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

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            • Primary Antibodies ›
            • KLF17 Antibodies

            NeoBiotechnologies

            KLF17/ ZNF393 Monoclonal Antibody (PCRP-KLF17-1G2)

            View all (14) KLF17 antibodies
            Datasheet
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            Datasheet
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            Cite KLF17/ ZNF393 Monoclonal Antibody (PCRP-KLF17-1G2)

            • Antibody Testing Data (3)
            Application
            KLF17/ ZNF393 Antibody in Flow Cytometry (Flow)
            Group 53 Created with Sketch.

            FIGURE: 1 / 3

            KLF17/ ZNF393 Antibody (128209-MSM1-P1ABX) in Flow

            Flow cytometric analysis of PFA-fixed HeLa cells. KLF17 Mouse Monoclonal Antibody (PCRP-KLF17-1G2) followed by goat anti-mouse IgG-CF488 (blue), un stained cells (red).
            View Product

            KLF17/ ZNF393 Antibody in Flow Cytometry (Flow)
            KLF17/ ZNF393 Antibody in Peptide array (ARRAY)
            KLF17/ ZNF393 Antibody in SDS-PAGE (SDS-PAGE)

            Product Details

            128209-MSM1-P1ABX

            Applications
            Tested Dilution
            Publications

            Western Blot (WB)

            1-2 µg/mL
            -

            Immunocytochemistry (ICC/IF)

            1-2 µg/mL
            -

            Flow Cytometry (Flow)

            1-2 µg/10^6 cells
            -

            Immunoprecipitation (IP)

            1-2 µg
            -

            Peptide Array (Array)

            Assay-dependent
            -
            Product Specifications

            Species Reactivity

            Human

            Host/Isotype

            Mouse / IgG2a

            Class

            Monoclonal

            Type

            Antibody

            Clone

            PCRP-KLF17-1G2

            Immunogen

            Recombinant full-length human KLF17protein
            View immunogen

            Conjugate

            Unconjugated

            Form

            Liquid

            Concentration

            1 mg/mL

            Purification

            Protein A/G

            Storage buffer

            PBS, pH 7.4

            Contains

            no preservative

            Storage conditions

            -20°C, Avoid Freeze/Thaw Cycles

            Shipping conditions

            Ambient (domestic); Wet ice (international)

            Target Information

            KLF17 is a transcription repressor that binds to the promoter of target genes and prevents their expression. Acts as a negative regulator of epithelial-mesenchymal transition and metastasis in breast cancer. Specifically binds the 5'-CACCC-3' sequence in the promoter of ID1, a key metastasis regulator in breast cancer, and repress its expression. May be a germ cell-specific transcription factor that plays important roles in spermatid differentiation and oocyte development.

            For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

            References (0)

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            Cite this product

            Bioinformatics

            Protein Aliases: FLJ40160; Krueppel-like factor 17; Kruppel-like factor 17; novel zinc-finger protein; Zinc finger protein 393; ZLF393

            View more View less

            Gene Aliases: KLF17; Zfp393; ZNF393

            View more View less

            UniProt ID: (Human) Q5JT82

            View more View less

            Entrez Gene ID: (Human) 128209

            View more View less

            Function(s)

            RNA polymerase II core promoter proximal region sequence-specific DNA binding transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding transcription factor activity, sequence-specific DNA binding protein binding transcription regulatory region DNA binding metal ion binding C2H2 zinc finger transcription factor

            Process(es)

            negative regulation of transcription from RNA polymerase II promoter transcription, DNA-templated regulation of transcription from RNA polymerase II promoter gamete generation
            It has to be done as per old AB suggested Products section.
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            Performance Guarantee

            If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

            Learn more
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            We're here to help

            Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.

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