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Nitrilotriacetic acid, trisodium salt, monohydrate, 99+%, Thermo Scientific Chemicals
Nitrilotriacetic acid, trisodium salt, monohydrate, CAS # 18662-53-8, is considered a non-genotoxic compound showing carcinogenic activity and is used as an inducer of tumorigenesis in laboratory studies using animal models.
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Catalog number 147845000
Price (USD)/ Each
50.65
Online exclusive
55.90 Save 5.25 (9%)
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Quantity:
500 g
Packaging:
Plastic bottle
Price (USD)/ Each
50.65
Online exclusive
55.90 Save 5.25 (9%)
Nitrilotriacetic acid, trisodium salt, monohydrate, 99+%, Thermo Scientific Chemicals
Catalog number147845000
Price (USD)/ Each
50.65
Online exclusive
55.90 Save 5.25 (9%)
-
Chemical Identifiers
CAS18662-53-8
IUPAC Nametrisodium 2-[bis(carboxylatomethyl)amino]acetate hydrate
Molecular FormulaC6H8NNa3O7
InChI KeyHERBOKBJKVUALN-UHFFFAOYSA-K
SMILESO.[Na+].[Na+].[Na+].[O-]C(=O)CN(CC([O-])=O)CC([O-])=O
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Specifications
Specification Sheet
Specification SheetAppearance (Color)White
Appearance (Form)Powder or crystals and/or chunks
Infrared spectrumConforms
Titration with HClO4>=99.0 %
This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
General Information
• Nitrilotriacetic acid, trisodium salt, monohydrate is considered to be a nongenotoxic compound with carcinogenic activity
• This compound inhibits gap-junctional communication between Chinese hamster lung fibroblasts
Applications
• Nitrilotriacetic acid trisodium salt monohydrate is commonly used in laboratory experiments due to its capacity to induce the tumorigenic process
• It has been used in in vivo experiments as an inducer of bladder and kidney tumors in animal models
• It is used as a chelating agent, which forms coordination compounds with metal ions (chelates)
Literature References
Malcolm, A.; Mills, L. Inhibition of gap-junctional intercellular communication between Chinese hamster lung fibroblasts by di(2-ethylhexyl) phthalate (DEHP) and trisodium nitrilotriacetate monohydrate (NTA). Cell Biology and Toxicology. 1989, 5, 145–153.
WARNING: Cancer – www.P65Warnings.ca.gov
RUO – Research Use Only
Dionisio, K.; Phillips, K.; Price, P.; Grulke, C.; Williams, A.; Biryol, D.; Hong, T.; Isaacs, K. The Chemical and products database, a resource for exposure-relevant data on chemicals in consumer products. Scientific Data. 2018, 5, 1-9.
Budunova, I.; Williams, G. Cell culture assays for chemicals with tumor-promoting or tumor-inhibiting activity based on the modulation of intercellular communication. Cell Biology and Toxicology. 1994, 10, 71-116.