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Product Details
23381-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
FBXO33 fusion protein Ag20055
Conjugate
Unconjugated
Form
Liquid
Concentration
0.4 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice
Product Specific Information
Immunogen sequence: DISVLQQQGS LSNTYLSKVD PDGKKIKQIQ QLFEEILSNS RQLKWLSCGF MLEIVTPTSL SSLSNAVANT MEHLSLLDNN IPGNSTLITA VELERFVNLH SLALDFCDFT AEMARVLTDS NHVPLQRLSL LVHNVSVMHK SLDNMPNDEH WKALSRKSTS FRVYIMAFDI KSEDMLKILK PSIPLERIHF DSYITCVSGA IVDLISRQYD KFLTHFILMN DVIDTSGFPD LSDNRNEDPL VLLAWRCTKL SLLAIHGYTV WAHNLIAIAR LRGSDLKVLE VTEESIDFDQ GELADQDVDP VHNLIEQVSL GLGQPWHAVM DIESLSVFTE PNRHFYREMQ SFSEDI
Target Information
FBXO33 is the substrate recognition component of a (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. FBXO33 probably recognizes and binds to phosphorylated target proteins. Recognizes YBX1.Members of the F-box protein family, such as FBXO33, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1, cullin, and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: AIG30-12-1; F-box only protein 33
Gene Aliases: 5730501N20Rik; AI642135; BMND12; c14_5247; FBX33; FBXO33
UniProt ID: (Human) Q7Z6M2, (Mouse) Q8VE08
Entrez Gene ID: (Human) 254170, (Rat) 314157, (Mouse) 70611
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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