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Immunogen sequence: KTYQHFTLEK AYLREDFFWA FTPAAGDFIR FRFFQPLRLE RFFFRSGNIE HPEDKLFNTS VEVLPFDNPQ SDKEALQEGR TATLRYPRSP DGYLQIGSFY KGVAEGEVDP AFGPLEALRL SIQTDSPVWV ILSEIFLKKA D
Glycosyltransferase that participates in the transfer of N-acetylglucosamine (GlcNAc) to the core mannose residues of N- linked glycans. Catalyzes the formation of the GlcNAcbeta1-4 branch on the GlcNAcbeta1-2Manalpha1-3 arm of the core structure of N-linked glycans. Essential for the production of tri- and tetra-antennary N-linked sugar chains. Has lower affinities for donors or acceptors than MGAT4A, suggesting that, under physiological conditions, it is not the main contributor in N- glycan biosynthesis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: 2.4.1.145; Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase B; alpha-1,3-mannosyl-glycoprotein beta-1,4-N-acetylglucosaminyltransferase; aminyltransferase; GlcNAc-T IVb; gnT-IVb; mannoside acetylglucosaminyltransferase 4, isoenzyme B; mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isoenzyme B; N-acetylglucosaminyltransferase IVb; N-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase IVb; UDP-N-acetylglucosamine: alpha-1,3-D-mannoside beta-1,4-N-acetylglucosaminyltransferase IV; UDP-N-acetylglucosamine: alpha-1,3-D-mannoside beta-1,4-N-acetylglucosaminyltransferase IVb
Gene Aliases: AA407995; GNT-IV; GNT-IVB; GnTIVb; MGAT4B; RGD1562836; UNQ906/PRO1927
UniProt ID: (Human) Q9UQ53, (Mouse) Q812F8
Entrez Gene ID: (Human) 11282, (Rat) 303100, (Mouse) 103534
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