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This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
General description
• Carbamazepine is an aromatic ring of the dibenzoazepine class that acts as a sodium channel blocker
• It is a tricyclic antidepressant-like drug that reduces post-tetanic potentiation
Applications
Carbamazepine can be used as a sodium channel blocker and as a glutamate-transporter agonist to reduce neural activity and produce inhibitory effects in the brain
Carbamazepine is useful in the research of pain, epilepsy, and manic depression
Ben-Menachem, E.; Grebe, H.P.; Terada, K.; Jensen, L.; Li, T.; De Backer, M.; Steiniger-Brach, B.; Gasalla, T.; Brock, M.; Biton, V. Long-term safety and efficacy of lacosamide and controlled-release carbamazepine monotherapy in patients with newly diagnosed epilepsy. Epilepsia. 2019, 60(12), 2437-2447. Erratum in: Epilepsia. 2021, 62(4), 1039.
Schmitz, B.; Dimova, S.; Zhang, Y.; Chellun, D.; De Backer, M.; Gasalla, T. Tolerability and efficacy of lacosamide and controlled-release carbamazepine monotherapy in patients with newly diagnosed epilepsy and concomitant psychiatric conditions: Post hoc analysis of a prospective, randomized, double-blind trial. Epilepsy Res. 2020, 159, 106220.