1-Naphthoic acid is used as an intermediate for the synthesis of pharmaceuticals, photochemicals, plant growth hormones, dyes and other organic compounds.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Applications
1-Naphthoic acid is used as an intermediate for the synthesis of pharmaceuticals, photochemicals, plant growth hormones, dyes and other organic compounds.
Solubility
Freely soluble in hot alcohol and ether. Slightly soluble in hot water.
Notes
Store away from oxidizing agents. Store in a cool, dry condition in well sealed containers.
RUO – Research Use Only
General References:
- Da-Gang Yu; Zhang-Jie Shi. Mutual activation: Suzuki-Miyaura coupling through direct cleavage of the sp2 C-O bond of naphtholate. Angewandte Chemie. International edition in English.2011, 50 (31), 7097-7100.
- Carolina Berdugo-Clavijo; Xiaoli Dong; Jung Soh; Christoph W Sensen; Lisa M Gieg. Methanogenic biodegradation of two-ringed polycyclic aromatic hydrocarbons. FEMS Microbiology Ecology. 2012, 81 (1), 124-133.
- The unprotected acid undergoes lithiation, e.g. with s-BuLi, by stereospecific 1,4-addition, providing a facile route to 1,1,2-trisubstituted 1,2-dihydronaphthalenes: J. Org. Chem., 61, 5206 (1996).