4-Cyanopyridine, 98%, Thermo Scientific Chemicals
4-Cyanopyridine, 98%, Thermo Scientific Chemicals
Thermo Scientific Chemicals

4-Cyanopyridine, 98%, Thermo Scientific Chemicals

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Catalog number A10286.36
also known as A10286-36
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500 g
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Price (USD)/ Each
81.65
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Ends: 31-Dec-2024
95.50 
Save 13.85 (15%)
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4-Cyanopyridine, 98%, Thermo Scientific Chemicals
Catalog numberA10286.36
Price (USD)/ Each
81.65
Special Offer
Online exclusive
Ends: 31-Dec-2024
95.50 
Save 13.85 (15%)
-
Add to cart
Chemical Identifiers
CAS100-48-1
IUPAC Namepyridine-4-carbonitrile
Molecular FormulaC6H4N2
InChI KeyGPHQHTOMRSGBNZ-UHFFFAOYSA-N
SMILESN#CC1=CC=NC=C1
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SpecificationsSpecification SheetSpecification Sheet
Appearance (Color)Colorless to white to cream to pale brown
FormCrystals or powder or crystalline powder or lumps or fused solid
Identification (FTIR)Conforms
Assay (GC)≥97.5%
Melting Point (clear melt)75.0-82.0?C
4-Cyanopyridine is used as an intermediate in organic synthesis and pharmaceutical substances like isonicotinylhydrazide, which is used in the treatment of tuberculosis. It is used as a precursor for the preparation of isonicotinic acid and 4-diemthylaminopyridine (DMAP). It is involved in the synthesis of 6-methyl-2-pyridin-4-yl-pyrimidin-4-ylamine by reacting with acetonitrile.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
4-Cyanopyridine is used as an intermediate in organic synthesis and pharmaceutical substances like isonicotinylhydrazide, which is used in the treatment of tuberculosis. It is used as a precursor for the preparation of isonicotinic acid and 4-diemthylaminopyridine (DMAP). It is involved in the synthesis of 6-methyl-2-pyridin-4-yl-pyrimidin-4-ylamine by reacting with acetonitrile.

Solubility
Soluble in water.

Notes
Incompatible with strong acids, strong bases and strong oxidizing agents.
RUO – Research Use Only

General References:

  1. Naika, R. M.; Kumar, B.; Prasad, S.; Chetty, A. A.; Asthana, A. Catalytic ligand exchange reaction between hexacyanoferrate(II) and 4-cyanopyridine applied to trace kinetic analysis of palladium(II). Microchem. J. 2015, 122, 82-88.
  2. Naik, R. M.; Asthana, A.; Yadav, S. B. S. Comparative study of the catalytic effect of Ag(I) and Hg(II) on the exchange of cyanide by 4-cyanopyridine in hexacyanoferrate(II): a kinetic approach. J. Iran. Chem. Soc. 2015, 12 (3), 519-528.