3-Phenylpropionaldehyde is used as a flavoring agent. It is also used in the preparation of cinnamaldehyde, 2-chloro hydrocinnamaldehyde by alfa chlorination and mixture of homopropargyl alcohols. It serves as a precursor for the synthesis of mixture of syn- and anti-beta-hydroxyallylsilanes by hydroboration of allenylsilane. It is also involved in the catalytic asymmetric cyanosilylation to prepare (2S)-2-hydroxy-4-phenylbutanenitrile. Further, it undergoes Henry reaction to form nitroaldols by reacting with nitromethane.
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Applications
3-Phenylpropionaldehyde is used as a flavoring agent. It is also used in the preparation of cinnamaldehyde, 2-chloro hydrocinnamaldehyde by alfa chlorination and mixture of homopropargyl alcohols. It serves as a precursor for the synthesis of mixture of syn- and anti-beta-hydroxyallylsilanes by hydroboration of allenylsilane. It is also involved in the catalytic asymmetric cyanosilylation to prepare (2S)-2-hydroxy-4-phenylbutanenitrile. Further, it undergoes Henry reaction to form nitroaldols by reacting with nitromethane.
Solubility
Miscible with chloroform, dichloromethane, ethyl acetate, alcohol and ether. Immiscible with water.
Notes
Incompatible with strong oxidizing agents and strong bases.
RUO – Research Use Only
General References:
- Durndell, L. J.; Wilson, K.; Lee, A. F. Platinum-catalysed cinnamaldehyde hydrogenation in continuous flow. RSC Adv. 2015, 5 (97), 80022-80026.
- Kashyap, B.; Phukan, P. CuI catalyzed Barbier type allylation of aldehyde in presence of S1,S2-dipyridin-2-yl ferrocene-1,1'-dicarbothioate as ligand. Indian J. Chem. 2015, 54, 662-670.