tert-butylamine is used as a precursor for the preparation of rubber accelerators, pharmaceuticals and dyes. It is employed in synthesis of N-tert-butyl-acetamide, isoquinolines, pyridines, decumbenine, sulfontes, sulfonamides and methyl beta-ketophosphonate. It is also used in the study the effect of amines in influencing atmospheric sulfuric acid - water nucleation, hydroamination of terminal alkynes and measuring the surface acidity of solid catalyst. It acts as an indicator molecule in the study of NMR -based pH determination method.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Applications
tert-butylamine is used as a precursor for the preparation of rubber accelerators, pharmaceuticals and dyes. It is employed in synthesis of N-tert-butyl-acetamide, isoquinolines, pyridines, decumbenine, sulfontes, sulfonamides and methyl beta-ketophosphonate. It is also used in the study the effect of amines in influencing atmospheric sulfuric acid - water nucleation, hydroamination of terminal alkynes and measuring the surface acidity of solid catalyst. It acts as an indicator molecule in the study of NMR -based pH determination method.
Solubility
Miscible with water, alcohol, ether, chloroform and organic solvents.
Notes
Air sensitive. Incompatible with strong oxidizing agents, strong acids and acid anhydrides.
RUO – Research Use Only
General References:
- Szabo, Z. I.; Reti, Z. Z.; Gagyi, L.; Kis, E. L.; Sipos, E. Simultaneous Quantification of Related Substances of Perindopril Tert-Butylamine Using a Novel Stability Indicating Liquid Chromatographic Method. J. Chromatogr. Sci. 2015, 53 (3), 424-430.
- Dobrzycki, L.; Taraszewska, p.; Boese, R.; Cyranski, M. K.; Cirkel, S. A. Towards Clathrates: Frozen States of Hydration of tert-Butylamine. Angew. Chem. Int. Ed. 2015, 54 (35), 10138-10144.