Sodium pyruvate is used in cell culture media as an additional source of energy. It acts as an antioxidant and finds protective effects against oxygen radicals. It serves as an intermediate in many metabolic pathways such as sugar metabolism. It is converted into acetyl coenzyme A and enters the trichloroacetic acid cycle. In addition, it is involved with amino acid metabolism and initiates the Kreb's cycle. It plays an important role as a free radical scavenger.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Applications
Sodium pyruvate is used in cell culture media as an additional source of energy. It acts as an antioxidant and finds protective effects against oxygen radicals. It serves as an intermediate in many metabolic pathways such as sugar metabolism. It is converted into acetyl coenzyme A and enters the trichloroacetic acid cycle. In addition, it is involved with amino acid metabolism and initiates the Kreb′s cycle. It plays an important role as a free radical scavenger.
Solubility
Soluble in water.
Notes
Store in a cool place. Incompatible with strong oxidizing agents.
RUO – Research Use Only
Asmus, C.; Mozziconacci, O.; Schöneich, C. Low-Temperature NMR Characterization of Reaction of Sodium Pyruvate with Hydrogen Peroxide. J. Phys. Chem. A 2015, 119 (6), 966-977.
Mitsopoulos, P.; Chang, Y. H.; Wai, T.; König, T.; Dunn, S. D.; Langer, T.; Madrenas, J. Stomatin-Like Protein 2 Is Required for In Vivo Mitochondrial Respiratory Chain Supercomplex Formation and Optimal Cell Function. Mol. Cell. Biol. 2015, 35 (10), 1838-1847.