2,5-Dichloroaniline was used in a study to develop a fast and sensitive quantitative method for the detection of some aniline derivatives by solid-phase microextraction in gas chromatography-mass spectrometry.
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Applications
2,5-Dichloroaniline was used in a study to develop a fast and sensitive quantitative method for the detection of some aniline derivatives by solid-phase microextraction in gas chromatography-mass spectrometry.
Solubility
Soluble in dilute hydrochloric acid.
Notes
Air & Light Sensitive, keep container tightly closed. Store in cool, dry conditions in well sealed containers.
RUO – Research Use Only
Sakurai, T.; Sundaralingam, M.; G. A. Jeffrey, G.A. A nuclear quadrupole resonance and X-ray study of the crystal structure of 2,5-dichloroaniline. Acta Cryst. 1963, 16, 354-363.
Evgen ev, M.I.; Evgen eva, I.I.; Garmonov,S. Yu.; Ismailova, R. N. Sorption-Chromatographic Determination of Aniline, 4-Chloroaniline, and 2,5-Dichloroaniline in Air. Journal of Analytical Chemistry. 2003, 58, (6), 542-547.
Nucleophilic displacement of the chloro-substituents has been carried out by heating with thiophenol in the presence of K2CO3 in NMP: J. Org. Chem., 56, 862 (1991).