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4-Methoxy-3-buten-2-one, tech. 90%, Thermo Scientific Chemicals
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Catalog number A11235.30
also known as A11235-30
Price (USD)/ Each
1,232.00
-
Quantity:
250 g
Price (USD)/ Each
1,232.00
4-Methoxy-3-buten-2-one, tech. 90%, Thermo Scientific Chemicals
Catalog numberA11235.30
Price (USD)/ Each
1,232.00
-
Chemical Identifiers
CAS4652-27-1
Specifications
Specification Sheet
Specification SheetAppearance (Color)Clear, colourless to pale yellow
Refractive Index1.4610 - 1.4690 @20?C
Formliquid
Assay (GC)> 88.0%
4-Methoxy-3-buten-2-one is an important precursor for the synthesis of 1-methoxy-3-trimethylsilyloxy-1,3-butadiene and the Danishefsky diene and its equivalent. It is widely used as a reactant in the synthesis of hydroisoquinoline derivatives. It is employed as an intermediate for the synthesis of manzamine.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Applications
4-Methoxy-3-buten-2-one is an important precursor for the synthesis of 1-methoxy-3-trimethylsilyloxy-1,3-butadiene and the Danishefsky diene and its equivalent. It is widely used as a reactant in the synthesis of hydroisoquinoline derivatives. It is employed as an intermediate for the synthesis of manzamine.
Solubility
Miscible with tetrahydrofuran, ether, acetonitrile and benzene.
Notes
Keep away from sources of ignition. Keep the container tightly closed in a dry and well-ventilated place.
4-Methoxy-3-buten-2-one is an important precursor for the synthesis of 1-methoxy-3-trimethylsilyloxy-1,3-butadiene and the Danishefsky diene and its equivalent. It is widely used as a reactant in the synthesis of hydroisoquinoline derivatives. It is employed as an intermediate for the synthesis of manzamine.
Solubility
Miscible with tetrahydrofuran, ether, acetonitrile and benzene.
Notes
Keep away from sources of ignition. Keep the container tightly closed in a dry and well-ventilated place.
RUO – Research Use Only
General References:
- Arylation of the lithio-derivative provides a route to 2-aryl--pyrones: Tetrahedron Lett., 21, 1197, 2773 (1980):
- Wan, J. P.; Lin, Y.; Hu, K.; Liu, Y. Metal-free synthesis of 1,3,5-trisubstituted benzenes by the cyclotrimerization of enaminones or alkynes in water. RSC Adv. 2014, 4 (39), 20499-20505.
- Iwado, T.; Hasegawa, K.; Sato, T.; Okada, M.; Sue, K.; Iwamura, H.; Hiaki, T. Mechanistic and Exploratory Investigations into the Synthesis of 1,3,5-Triaroylbenzenes from 1-Aryl-2-propyn-1-ones and 1,3,5-Triacetylbenzene from 4-Methoxy-3-buten-2-one by Cyclotrimerization in Hot Water in the Absence of Added Acid or Base. J. Org. Chem. 2013 78 (5), 1949-1954.