D-(-)-Penicillamine, 98%, Thermo Scientific Chemicals
D-(-)-Penicillamine, 98%, Thermo Scientific Chemicals
Thermo Scientific Chemicals

D-(-)-Penicillamine, 98%, Thermo Scientific Chemicals

Have Questions?
Change viewbuttonViewtableView
Quantity:
25 g
5 g
100 g
This chemical may require us to obtain additional information for our regulatory and chemical compliance records. If required, we will contact you for this information once your order is placed.
Catalog number A11446.14
also known as A11446-14
Price (USD)/ Each
253.00
-
Add to cart
Quantity:
25 g
Request bulk or custom format
Price (USD)/ Each
253.00
Add to cart
D-(-)-Penicillamine, 98%, Thermo Scientific Chemicals
Catalog numberA11446.14
Price (USD)/ Each
253.00
-
Add to cart
Chemical Identifiers
CAS52-67-5
IUPAC Name(2S)-2-amino-3-methyl-3-sulfanylbutanoic acid
Molecular FormulaC5H11NO2S
InChI KeyVVNCNSJFMMFHPL-VKHMYHEASA-N
SMILESCC(C)(S)[C@@H](N)C(O)=O
View more
SpecificationsSpecification SheetSpecification Sheet
FormPowder
Assay (Non-aqueous acid-base Titration)≥97.5 to ≤102.5%
Appearance (Color)White to pale cream
Optical Rotation-62.5? ? 2? (c=5%, 1N NaOH)
It is used mainly as chelating agent in heavy metal poisoning as in lead, mercury and copper poisoning. It is used in Wilson's disease. It  is used in pharmacy as chelating agent and as immunosuppressant for treating rheumatoid arthritis by reducing the number of T cells, inhibiting the macrophages, by reducing the activity of Interleukin 1 and rheumatoid factor and in preventing crosslinking of the collagen. It acts as an exogenous NOS modulator.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Solubility
It is freely soluble in water, slightly soluble in alcohol, insoluble in chloroform, ether, acetone, benzene, and in carbon tetrachloride.

Notes
Stable under normal conditions. Incompatabile to strong oxidizing agents. Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Recommended storage temperature: 2 - 8°C.
WARNING: Reproductive Harm - www.P65Warnings.ca.gov
RUO – Research Use Only

General References:

  1. Henri Brunner.; Richard Becker.; Georg Riepl. Asymmetric syntheses. 20. Enantioselective hydrosilylation of ketones with [Rh(cod)Cl]2/thiazolidine catalysts. Organometallics.19843, (9), 1354-1359.
  2. Joseph Wang.; Teresa Golden.; Kurian Varughese.; Ibrahim El-Rayes. Polishable and robust modified graphite epoxy electrodes. Anal. Chem.198961, (5), 508-512.