Thermo Scientific Chemicals

Hypoxanthine, 99%, Thermo Scientific Chemicals

Catalog number: A11481.06
5 g, Each
Thermo Scientific Chemicals

Hypoxanthine, 99%, Thermo Scientific Chemicals

Catalog number: A11481.06
5 g, Each
Quantity
Catalog number: A11481.06
also known as A11481-06
Price (USD)
Quantity
-
Have Questions?

Chemical Identifiers

CAS
68-94-0
IUPAC Name
6,7-dihydro-3H-purin-6-one
Molecular Formula
C5H4N4O
InChI Key
FDGQSTZJBFJUBT-UHFFFAOYSA-N
SMILES
O=C1N=CNC2=C1NC=N2
Form
Powder or lumps
Assay (HPLC)
≥98.5%
Appearance (Color)
White to pale cream
Assay (Non-aqueous acid-base Titration)
≥98.5 to ≤101.5%

Description

Hypoxanthine, is used as a marker for energy perturbation in hypoxia/ ischemia. It has been also used in DNA studies to investigate the destabilizing effect it has on DNA duplexes containing hypoxanthine as a base, in a gas phase versus a liquid phase. Hypoxanthine has also been used in studies along with 8-oxoguanine nucleotides to investigate their interaction with human DNA pol A (DNA polymerase alpha) and DNA polymerase I from Bacillus stearothermophilus. It is also used as a pharmaceutical intermediate.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Hypoxanthine, is used as a marker for energy perturbation in hypoxia/ ischemia. It has been also used in DNA studies to investigate the destabilizing effect it has on DNA duplexes containing hypoxanthine as a base, in a gas phase versus a liquid phase. Hypoxanthine has also been used in studies along with 8-oxoguanine nucleotides to investigate their interaction with human DNA pol å (DNA polymerase alpha) and DNA polymerase I from Bacillus stearothermophilus. It is also used as a pharmaceutical intermediate.

Solubility
It does not mix appreciably with water (1:1400). Small octahedra crystals from water.

Notes
Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Incompatible to Strong oxidizing agents. Stable under recommended storage conditions. Sterilize by filtration through a 0.22 µm filter.
RUO – Research Use Only

Figures

Documents & Downloads

Certificates

    Frequently asked questions (FAQs)

    Citations & References

    Search citations by name, author, journal title or abstract text