3-Bromo-4-methylbenzoic acid has been used in the synthesis of biphenyl amides, 2-benzazepine-4-acetic acid derivative, as an analog of the potent, nonpeptide GPIIb/IIIa antagonist, O-spiro C-aryl glucosides. It is also used as catalytic agent and petrochemical additive.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Applications
3-Bromo-4-methylbenzoic acid has been used in the synthesis of biphenyl amides, 2-benzazepine-4-acetic acid derivative, as an analog of the potent, nonpeptide GPIIb/IIIa antagonist, O-spiro C-aryl glucosides. It is also used as catalytic agent and petrochemical additive.
Solubility
Soluble in methanol. Insoluble in water.
Notes
Store in a cool, dry, well-ventilated area away from incompatible substances such as oxidizing agents.
RUO – Research Use Only
Baihua Xu; Binhua Lv; Yan Feng; Ge Xu; Jiyan Du; Ajith Welihinda; Zelin Sheng; Brian Seed; Yuanwei Chen. O-SpiroC-aryl glucosides as novel sodium-dependent glucose co-transporter 2 (SGLT2) inhibitors. Bioorganic & Medicinal Chemistry Letters.2009, 19 (19), 5632-5635.
Richard M Angell; Tony D Angell; Paul Bamborough; David Brown; Murray Brown; Jacky B Buckton; Stuart G Cockerill; Chris D Edwards; Katherine L Jones; Tim Longstaff; Penny A Smee; Kathryn J Smith; Don O Somers; Ann L Walker; Malcolm Willson. Biphenyl amide p38 kinase inhibitors 2: Optimisation and SAR. Bioorganic & Medicinal Chemistry Letters.2008, 18 (1), 324-328.