Chlorotriphenylmethane is used as laboratory chemical. It acts as a protecting reagent for thiols, alcohols and amines. It is used in organic synthesis for initiating trityl group protection and for preparing S-trityl-L-cysteine (STLC), a inhibitor of Eg5 prevents mitotic progression.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Applications
Chlorotriphenylmethane is used as laboratory chemical. It acts as a protecting reagent for thiols, alcohols and amines. It is used in organic synthesis for initiating trityl group protection and for preparing S-trityl-L-cysteine (STLC), a inhibitor of Eg5 prevents mitotic progression.
Solubility
Insoluble in water. Soluble in chloroform, hexane, benzene, ether, acetone and tetrahydrofuran.
Notes
Incompatible with strong oxidizing agents.
RUO – Research Use Only
General References:
- Wang, R.; Jiang, X.; He, A.; Xiang, T.; Zhao, C. An in situ crosslinking approach towards chitosan-based semi-IPN hybrid particles for versatile adsorptions of toxins. RSC Adv. 2015, 5 (64), 51631-51641.
- Huang, P.; Lin, L.; Yang, D.; Hong, J. Rigid Jeffamine-included polyrotaxane as hydrogen-bond template for salicylideneazine with aggregation-enhanced emission. RSC Adv. 2015, 5 (48), 37979-37987.