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2-Deoxy-D-ribose, 99%
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Catalog number A11990.06
also known as A11990-06
Price (USD)/ Each
64.65
Online exclusive
71.30 Save 6.65 (9%)
-
Quantity:
5 g
Price (USD)/ Each
64.65
Online exclusive
71.30 Save 6.65 (9%)
2-Deoxy-D-ribose, 99%
Catalog numberA11990.06
Price (USD)/ Each
64.65
Online exclusive
71.30 Save 6.65 (9%)
-
Chemical Identifiers
CAS533-67-5
IUPAC Name(4S,5R)-5-(hydroxymethyl)oxolane-2,4-diol
Molecular FormulaC5H10O4
InChI KeyPDWIQYODPROSQH-GLULIZFNNA-N
SMILESOC[C@H]1OC(O)C[C@@H]1O
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Specifications
Specification Sheet
Specification SheetAppearance (Color)White to cream or pale yellow
FormPowder
Assay from Supplier's CofA≥98.5 area-% (HPLC)
Identification (FTIR)Conforms
Optical Rotation-59.0° to -54.0° (c=1 in water, 24hr)
2-Deoxy-D-ribose is used as a precursor to deoxyribonucleic acid. It induces apoptosis by inhibiting the synthesis and increasing the efflux of glutathione. Further, it is used in the synthesis of optically active dipyrrolyl alkanols from pyrroles on the surface of montmorillonite KSF clay.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Applications
2-Deoxy-D-ribose is used as a precursor to deoxyribonucleic acid. It induces apoptosis by inhibiting the synthesis and increasing the efflux of glutathione. Further, it is used in the synthesis of optically active dipyrrolyl alkanols from pyrroles on the surface of montmorillonite KSF clay.
Solubility
Soluble in water.
Notes
Store in a cool place. Incompatible with strong oxidizing agents.
2-Deoxy-D-ribose is used as a precursor to deoxyribonucleic acid. It induces apoptosis by inhibiting the synthesis and increasing the efflux of glutathione. Further, it is used in the synthesis of optically active dipyrrolyl alkanols from pyrroles on the surface of montmorillonite KSF clay.
Solubility
Soluble in water.
Notes
Store in a cool place. Incompatible with strong oxidizing agents.
RUO – Research Use Only
General References:
- Starting material for a free-radical coupling reaction (employing homolytic fission of a derivative with 2-Mercaptopyridine N-oxide, A14152) which provides a facile preparative method for C-nucleosides: Chem. Lett., 1673 (1992).
- Koh, G.; Yang, E. J.; Kim, J. Y.; Hyun, J.; Yoo, S.; Lee, S. A. Intracellular glutathione production, but not protein glycation, underlies the protective effects of captopril against 2‑deoxy‑D‑ribose‑induced beta‑cell damage. Mol. Med. Rep. 2015, 12 (4), 5314-5320.
- Azofra, L. M.; Quesada-Moreno, M. M.; Alkorta, I.; Avilés-Moreno, J. R.; López-González, J. J.; Elguero, J. Carbohydrates in the gas phase: conformational preference of d-ribose and 2-deoxy-d-ribose. New J. Chem. 2014, 38 (2), 529-538.