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1-Phenyl-3-pyrazolidinone, 97%, Thermo Scientific Chemicals
Catalog number: A12089.0B
1000 g, Each
Thermo Scientific Chemicals
1-Phenyl-3-pyrazolidinone, 97%, Thermo Scientific Chemicals
Catalog number: A12089.0B
1000 g, Each
Quantity
Catalog number: A12089.0B
also known as A12089-0B
Price (EUR)
334,64 Online price
376,00
Each
Quantity
-
Chemical Identifiers
CAS
92-43-3
IUPAC Name
1-phenylpyrazolidin-3-one
Molecular Formula
C9H10N2O
InChI Key
CMCWWLVWPDLCRM-UHFFFAOYSA-N
SMILES
O=C1CCN(N1)C1=CC=CC=C1
Specifications
Specification SheetAppearance (Color)
White to cream to pale brown
Form
Crystals or powder or crystalline powder
Assay (GC)
≥96.0%
Melting Point (clear melt)
115.5-124.5?C
Description
Phenidone inhibits both the LO (lipoxygenase) and Cox (cyclooxygenase) pathways, the synthesis of Fos-related antigen protein, and is described as an anti-inflammatory and anti-oxidant compound. Phenidone has been shown to block neurotoxicity induced by kainate, and weakens oxidative stress induced by lipopolysaccharide.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Applications
Phenidone inhibits both the LO (lipoxygenase) and Cox (cyclooxygenase) pathways, the synthesis of Fos-related antigen protein, and is described as an anti-inflammatory and anti-oxidant compound. Phenidone has been shown to block neurotoxicity induced by kainate, and weakens oxidative stress induced by lipopolysaccharide.
Solubility
Soluble in water (1:10 hot), methanol (0.1 mg/mL), DMSO (75 mg/mL), and ethanol.
Notes
Store in cool place. Keep away from oxidizing agents.
Phenidone inhibits both the LO (lipoxygenase) and Cox (cyclooxygenase) pathways, the synthesis of Fos-related antigen protein, and is described as an anti-inflammatory and anti-oxidant compound. Phenidone has been shown to block neurotoxicity induced by kainate, and weakens oxidative stress induced by lipopolysaccharide.
Solubility
Soluble in water (1:10 hot), methanol (0.1 mg/mL), DMSO (75 mg/mL), and ethanol.
Notes
Store in cool place. Keep away from oxidizing agents.
RUO – Research Use Only
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Safety and Handling
Classification of the substance or mixture
CLP classification - Regulation(EC) No 1272/2008
Acute oral toxicity
Category 4
Chronic aquatic toxicity
Category 2
Label Elements
Signal Word
Warning
Hazard Statements
H302 - Harmful if swallowed
H411 - Toxic to aquatic life with long lasting effects
Precautionary Statements
P273 - Avoid release to the environment
P301 + P310 - IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician