N,N,N',N'-Tetramethyl-p-phenylenediamine dihydrochloride, 98+%, Thermo Scientific Chemicals
N,N,N',N'-Tetramethyl-p-phenylenediamine dihydrochloride, 98+%, Thermo Scientific Chemicals
Thermo Scientific Chemicals

N,N,N',N'-Tetramethyl-p-phenylenediamine dihydrochloride, 98+%, Thermo Scientific Chemicals

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Catalog number A12107.09
also known as A12107-09
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10 g
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Price (USD)/ Each
63.65
Online exclusive
70.50 
Save 6.85 (10%)
Add to cart
N,N,N',N'-Tetramethyl-p-phenylenediamine dihydrochloride, 98+%, Thermo Scientific Chemicals
Catalog numberA12107.09
Price (USD)/ Each
63.65
Online exclusive
70.50 
Save 6.85 (10%)
-
Add to cart
Chemical Identifiers
CAS637-01-4
IUPAC Namedihydrogen N1,N1,N4,N4-tetramethylbenzene-1,4-diamine dichloride
Molecular FormulaC10H18Cl2N2
InChI KeyFBHKTSXMTASXFJ-UHFFFAOYSA-N
SMILES[H+].[H+].[Cl-].[Cl-].CN(C)C1=CC=C(C=C1)N(C)C
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SpecificationsSpecification SheetSpecification Sheet
Assay (Freebase GC)≥98.0% (non-U.S. Specification)
Appearance (Color)White to cream to yellow or grey or pale brown
Assay (Titration ex Chloride)≥98.0 to ≤102.0% (non-U.S. Specification)
FormCrystals or powder or crystalline powder
Assay from Supplier's CofA≥98.0% (U.S. Specification )
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N,N,N',N'-tetramethyl-p-phenylenediamine dihydrochloride (TMPD) is an oxidizable compound that serves as a reducing co-substrate for heme peroxidases. It is also used as a test reagent in microbiology for the classification of cytochrome oxidase positive aerobic microorganisms. It finds application as a detection of peroxidases on polyacrylamide gels.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
N,N,N′,N′-tetramethyl-p-phenylenediamine dihydrochloride (TMPD) is an oxidizable compound that serves as a reducing co-substrate for heme peroxidases. It is also used as a test reagent in microbiology for the classification of cytochrome oxidase positive aerobic microorganisms. It finds application as a detection of peroxidases on polyacrylamide gels.

Solubility
Soluble in dimethyl sulfoxide, water and phosphate buffered saline at pH 7.2.

Notes
Light sensitive. Incompatible with strong oxidizing agents.                    
RUO – Research Use Only

General References:

  1. Zoll, J.; Bouitbir, J.; Sirvent, P.; Klein, A.; Charton, A.; Jimenez, L.; Péronnet, F. R.; Geny, B.; Richard, R. apparent Km of mitochondria for oxygen computed from Vmax measured in permeabilized muscle fibers is lower in water enriched in oxygen by electrolysis than injection. Drug Des. Devel. Ther. 2015, 9, 3589-3597.
  2. Lejay, A.; Choquet, P.; Thaveau, F.; Singh, F.; Schlagowski, A.; Charles, A. L.; Laverny, G.; Metzger, D.; Zoll, J.; Chakfe, N. A New Murine Model of Sustainable and Durable Chronic Critical Limb Ischemia Fairly Mimicking Human Pathology. Eur. J. Vasc. Endovasc. 2015, 49 (2), 205-212.