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Trifluoroacetic acid, 99%, Thermo Scientific Chemicals
Catalog number: A12198.36
500 g, Each
Thermo Scientific Chemicals
Trifluoroacetic acid, 99%, Thermo Scientific Chemicals
Catalog number: A12198.36
500 g, Each
Quantity
Catalog number: A12198.36
Price (USD)
Special offer:
144.65 170.00 Save 25.35 (14%)
Ends: 15-Oct-2024
Each
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Chemical Identifiers
CAS
76-05-1
IUPAC Name
trifluoroacetic acid
Molecular Formula
C2HF3O2
InChI Key
DTQVDTLACAAQTR-UHFFFAOYSA-N
SMILES
OC(=O)C(F)(F)F
Specifications
Specification SheetAssay from Supplier's CofA
≥98.5% (US-sourced material)
Water Content (Karl Fischer Titration)
≤0.5%
Appearance (Color)
Clear colorless to pale yellow
Assay (Aqueous acid-base Titration)
≥98.5 to ≤101.5% (UK-sourced material)
Comment
Material sourced in UK and US
Description
The combination of properties like solubility in most of the solvents, volatility, catalytic property, and strong acidity with non-oxidizing nature makes it a widely used reagent in organic synthesis. Trifluoroacetic acid is an important building block in the synthesis of pharmaceuticals, agrochemicals and performance products. It is a precursor to many fluorinated compounds, and widely used in peptide synthesis and other organic transformations involving deprotection of t-BOC group. TFA finds use as an ion pairing agent in liquid chromatography, as a solvent in NMR spectroscopy and as a calibrant in mass spectrometry.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Applications
The combination of properties like solubility in most of the solvents, volatility, catalytic property, and strong acidity with non-oxidizing nature makes it a widely used reagent in organic synthesis. Trifluoroacetic acid is an important building block in the synthesis of pharmaceuticals, agrochemicals and performance products. It is a precursor to many fluorinated compounds, and widely used in peptide synthesis and other organic transformations involving deprotection of t-BOC group. TFA finds use as an ion pairing agent in liquid chromatography, as a solvent in NMR spectroscopy and as a calibrant in mass spectrometry.
Solubility
Miscible with ether, acetone, ethanol, benzene, hexane, and CCl4
Notes
Trifluoroacetic acid (TFA) is a stable, hygroscopic, volatile and low-boiling organic acid. Storage in a cool place is recommended.
The combination of properties like solubility in most of the solvents, volatility, catalytic property, and strong acidity with non-oxidizing nature makes it a widely used reagent in organic synthesis. Trifluoroacetic acid is an important building block in the synthesis of pharmaceuticals, agrochemicals and performance products. It is a precursor to many fluorinated compounds, and widely used in peptide synthesis and other organic transformations involving deprotection of t-BOC group. TFA finds use as an ion pairing agent in liquid chromatography, as a solvent in NMR spectroscopy and as a calibrant in mass spectrometry.
Solubility
Miscible with ether, acetone, ethanol, benzene, hexane, and CCl4
Notes
Trifluoroacetic acid (TFA) is a stable, hygroscopic, volatile and low-boiling organic acid. Storage in a cool place is recommended.
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