4-Methoxy-o-phenylenediamine is widely used as an intermediate in organic synthesis and pharmaceuticals. It is an important precursor for the synthesis of other heterocyclic compounds. It is used in the determination of glyoxal, methylglyoxal, and diacetyl in urine using 4-methoxy-o-phenylenediamine as derivatizing reagent by High-performance liquid chromatography (HPLC).
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Applications
4-Methoxy-o-phenylenediamine is widely used as an intermediate in organic synthesis and pharmaceuticals. It is an important precursor for the synthesis of other heterocyclic compounds. It is used in the determination of glyoxal, methylglyoxal, and diacetyl in urine using 4-methoxy-o-phenylenediamine as derivatizing reagent by High-performance liquid chromatography (HPLC).
Solubility
Soluble in water.
Notes
Store in a cool place. Incompatible with acids, acid chlorides, acid anhydrides, chloroformates and strong oxidizing agents. Hygroscopic.
RUO – Research Use Only
General References:
- Escobosa, A. R. C.; Ojeda, A. G.; Wrobel, K.; Magana, A. A.; Wrobel, K. Methylglyoxal is associated with bacteriostatic activity of high fructose agave syrups. Food Chem. 2014, 165, 444-450.
- Ojeda, A. G.; Escobosa, A. R. C.; Wrobel, K.; Barrientos, E. Y.; Wrobel, K. Effect of Cd(II) and Se(IV) exposure on cellular distribution of both elements and concentration levels of glyoxal and methylglyoxal in Lepidium sativum. Metallomics 2013, 5 (9), 1254-1261.