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4-Aminopyridine, 98%, Thermo Scientific Chemicals
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Catalog number A12405.0B
also known as A12405-0B
Price (USD)/ Each
931.00
-
Quantity:
1000 g
Price (USD)/ Each
931.00
4-Aminopyridine, 98%, Thermo Scientific Chemicals
Catalog numberA12405.0B
Price (USD)/ Each
931.00
-
Chemical Identifiers
CAS504-24-5
IUPAC Namepyridin-4-amine
Molecular FormulaC5H6N2
InChI KeyNUKYPUAOHBNCPY-UHFFFAOYSA-N
SMILESNC1=CC=NC=C1
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Specifications
Specification Sheet
Specification SheetAppearance (Color)White to cream
Assay (Non-aqueous acid-base Titration)≥97.5 to ≤102.5%
Melting Point (clear melt)155.0-162.0?C
FormCrystals or powder or crystalline powder
Assay (GC)≥97.5%
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It is used as a research tool, in characterizing subtypes of the potassium channel. It has also been used as a drug, to manage some of the symptoms of multiple sclerosis. In the laboratory, 4-AP is a useful pharmacological tool in studying various potassium conductances in physiology and biophysics. Spinal cord injury patients have also seen improvement with 4-AP therapy.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Solubility
Soluble in water(112 g/L at 20 deg C). Soluble in ethyl ether, benzene. Slightly soluble in ligroin. Very soluble in ethanol. Soluble in methanol, acetone, tetrahydrofuran, isopropanol, acetonitrile, N,N-dimethylformamide, dimethylsulfoxide, and ethanol.
Notes
Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Store away from strong oxidizing agents.
Soluble in water(112 g/L at 20 deg C). Soluble in ethyl ether, benzene. Slightly soluble in ligroin. Very soluble in ethanol. Soluble in methanol, acetone, tetrahydrofuran, isopropanol, acetonitrile, N,N-dimethylformamide, dimethylsulfoxide, and ethanol.
Notes
Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Store away from strong oxidizing agents.
RUO – Research Use Only
General References:
- H Bostock et. al.The effects of 4-aminopyridine and tetraethylammonium ions on normal and demyelinated mammalian nerve fibres. Journal of Physiology. 1981, 313 301-315.
- Shun-ichi Yamaguchi,; Michael A. Rogawski.Effects of anticonvulsant drugs on 4-aminopyridine-induced seizures in mice . Epilepsy Research. 1992, 11(1), 9-16.