Cyanoacetamide, 99%, Thermo Scientific Chemicals
Cyanoacetamide, 99%, Thermo Scientific Chemicals
Thermo Scientific Chemicals

Cyanoacetamide, 99%, Thermo Scientific Chemicals

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Quantity:
2500 g
100 g
500 g
Catalog number A12482.0E
also known as A12482-0E
Price (USD)/ Each
309.65
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Ends: 31-Dec-2024
364.00 
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Quantity:
2500 g
Request bulk or custom format
Price (USD)/ Each
309.65
Special Offer
Online exclusive
Ends: 31-Dec-2024
364.00 
Save 54.35 (15%)
Add to cart
Cyanoacetamide, 99%, Thermo Scientific Chemicals
Catalog numberA12482.0E
Price (USD)/ Each
309.65
Special Offer
Online exclusive
Ends: 31-Dec-2024
364.00 
Save 54.35 (15%)
-
Add to cart
Chemical Identifiers
CAS107-91-5
SpecificationsSpecification SheetSpecification Sheet
FormCrystals or powder or crystalline powder
Melting Point (clear melt)118-123?C
Assay (GC)≥98.5%
Appearance (Color)White to pale cream
Identification (FTIR)Conforms
Cyanoacetamide was used in spectrofluorimetric method for the determination of some antihistaminic H1 receptor antagonist drugs such as ebastine, cetirizine dihydrochloride and fexofenadine hydrochloride. It may be used in fluorometric determination of 3,4-dihydroxyphenylalanine. It was used as post column fluorigenic derivatizing agent for the bio-analysis and pharmacokinetics of chitosan ester in rabbit serum. Cyanoacetamide is the starting reagent for vitamin B6 synthesis. It reacts with reducing carbohydrates in borate buffer to give intense fluorescence andis useful for the automated analysis of carbohydrates as borate complexes.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Cyanoacetamide was used in spectrofluorimetric method for the determination of some antihistaminic H1 receptor antagonist drugs such as ebastine, cetirizine dihydrochloride and fexofenadine hydrochloride. It may be used in fluorometric determination of 3,4-dihydroxyphenylalanine. It was used as post column fluorigenic derivatizing agent for the bio-analysis and pharmacokinetics of chitosan ester in rabbit serum. Cyanoacetamide is the starting reagent for vitamin B6 synthesis. It reacts with reducing carbohydrates in borate buffer to give intense fluorescence andis useful for the automated analysis of carbohydrates as borate complexes.

Solubility
Soluble in water.

Notes
Store under cool dry place. Ensure good ventilation. Incompatible with oxidizing agents.
RUO – Research Use Only

General References:

  1. Fadda AA, et al..; Turk. J. Cyanoacetamide derivatives as synthons in heterocyclic synthesis. J. Chem. 2008, 32 (3),259-286.
  2. Honda S, et al. Fluorimetric determination of reducing carbohydrates with 2-cyanoacetamide and application to automated analysis of carbohydrates as borate complexes. Anal. Chem. 1980, 52 (7), 1079-1082.
  3. Review of utility in heterocyclic synthesis: Heterocycles, 24, 2023 (1986). Reaction with various enones and enals in the presence of KO-t-Bu and oxygen in DMSO provides a one-step route to functionalized 3-cyano-2-pyridones: Tetrahedron Lett., 36, 3307 (1995):
  4. In the absence of oxygen, only Michael addition occurs.