O-Acetylsalicylic acid, 99%, Thermo Scientific Chemicals
O-Acetylsalicylic acid, 99%, Thermo Scientific Chemicals
Thermo Scientific Chemicals

O-Acetylsalicylic acid, 99%, Thermo Scientific Chemicals

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Quantity:
500 g
100 g
2500 g
Catalog number A12488.36
also known as A12488-36
Price (USD)/ Each
100.65
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112.00 
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Quantity:
500 g
Request bulk or custom format
Price (USD)/ Each
100.65
Online exclusive
112.00 
Save 11.35 (10%)
Add to cart
O-Acetylsalicylic acid, 99%, Thermo Scientific Chemicals
Catalog numberA12488.36
Price (USD)/ Each
100.65
Online exclusive
112.00 
Save 11.35 (10%)
-
Add to cart
Chemical Identifiers
CAS50-78-2
IUPAC Name2-(acetyloxy)benzoic acid
Molecular FormulaC9H8O4
InChI KeyBSYNRYMUTXBXSQ-UHFFFAOYSA-N
SMILESCC(=O)OC1=CC=CC=C1C(O)=O
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SpecificationsSpecification SheetSpecification Sheet
FormCrystals or powder or crystalline powder or granules or fused solid
Melting Point (clear melt)133.0-140.0?C
Appearance (Color)White
Identification (FTIR)Conforms
Assay (Aqueous acid-base Titration)≥98.5 to ≤101.5% (on dried substance)
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O-Acetylsalicylic acid is the prototypical analgesic used in the treatment of mild to moderate pain. acts as an inhibitor of cyclooxygenase which results in the inhibition of the biosynthesis of prostaglandins. Aspirin also inhibits platelet aggregation and is used in the prevention of arterial and venous thrombosis. Along with sodium salicylate (sc-3520), aspirin has been shown to block the long terminal repeat from the human immunodeficiency virus and the Ig κ enhancer from NFκB dependent transcription.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
O-Acetylsalicylic acid is the prototypical analgesic used in the treatment of mild to moderate pain. acts as an inhibitor of cyclooxygenase which results in the inhibition of the biosynthesis of prostaglandins. Aspirin also inhibits platelet aggregation and is used in the prevention of arterial and venous thrombosis. Along with sodium salicylate (sc-3520), aspirin has been shown to block the long terminal repeat from the human immunodeficiency virus and the Ig κ enhancer from NFκB dependent transcription.

Solubility
Soluble in 100% ethanol (80mg/ml), DMSO (41mg/ml) or dimethyl formamide (30mg/ml); slightly soluble in Phosphate-buffered saline (PBS), pH 7.2 (2.7mg/ml).

Notes
Store at room temperature. Ensure good ventilation.
WARNING: Reproductive Harm - www.P65Warnings.ca.gov
RUO – Research Use Only

General References:

  1. D W Gilroy et. Al. Differential effects of inhibitors of cyclooxygenase (cyclooxygenase 1 and cyclooxygenase 2) in acute inflammation. Eur. J. Pharmacol. 1998, 355 (2-3),211-217.
  2. K Schrör. Aspirin and platelets: the antiplatelet action of aspirin and its role in thrombosis treatment and prophylaxis. Seminars in Thrombosis and Hemostasis. 1997, 23 (4),349-356.