Thermo Scientific Chemicals

Hexaethyl phosphorous triamide, 97%, Thermo Scientific Chemicals

Catalog number: A12490.14
25 g, Each
Thermo Scientific Chemicals

Hexaethyl phosphorous triamide, 97%, Thermo Scientific Chemicals

Catalog number: A12490.14
25 g, Each
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Catalog number: A12490.14
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Chemical Identifiers

CAS
2283-11-6
IUPAC Name
[bis(diethylamino)phosphanyl]diethylamine
Molecular Formula
C12H30N3P
InChI Key
FDIOSTIIZGWENY-UHFFFAOYSA-N
SMILES
CCN(CC)P(N(CC)CC)N(CC)CC
Form
Liquid
Appearance (Color)
Clear or slightly hazy, colorless to yellow
Assay (GC)
>96.0%
Comment
May form small amount of sediment upon storage.
Refractive Index
1.4715-1.4765 @ 20?C

Description

Hexaethyl phosphorous triamide is used in the Barton syntheses of hindered alkenes, involving desulfurization of small-ring heterocycles with elimination of nitrogen or carbon dioxide. It is also used as a reagent for selective vicinal dehalogenation of halogenated alkanes to give perhalogenated alkenes. The method has potential for the synthesis of highly fluorinated and mixed fluoro-halo alkenes.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Hexaethyl phosphorous triamide is used in the Barton syntheses of hindered alkenes, involving desulfurization of small-ring heterocycles with elimination of nitrogen or carbon dioxide. It is also used as a reagent for selective vicinal dehalogenation of halogenated alkanes to give perhalogenated alkenes. The method has potential for the synthesis of highly fluorinated and mixed fluoro-halo alkenes.

Solubility
Insoluble in water.

Notes
Keep container tightly sealed. Store in cool, dry conditions in well sealed containers. Incompatible with oxidizing agents. It is sensitive to air. Store under dry inert gas.
RUO – Research Use Only

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