Thermo Scientific Chemicals

1-(Trimethylsilyl)imidazole, 97%, Thermo Scientific Chemicals

Catalog number: A12512.22
100 g, Each
Thermo Scientific Chemicals

1-(Trimethylsilyl)imidazole, 97%, Thermo Scientific Chemicals

Catalog number: A12512.22
100 g, Each
Quantity
Catalog number: A12512.22
also known as A12512-22
Price (USD)
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Chemical Identifiers

CAS
18156-74-6
IUPAC Name
1-(trimethylsilyl)-1H-imidazole
Molecular Formula
C6H12N2Si
InChI Key
YKFRUJSEPGHZFJ-UHFFFAOYSA-N
SMILES
C[Si](C)(C)N1C=CN=C1
Appearance (Color)
Clear colorless to pale yellow
Assay (GC)
≥96.0%
Identification (FTIR)
Conforms
Refractive Index
1.4740-1.4790 @ 20?C
Form
Liquid

Description

1-(Trimethylsilyl)imidazole acts as a silylating agent for alcohols, carbohydrates and 1,3-dicarbonyl compounds. It is a derivatization reagent used for selective silylation of hydroxyl groups and carboxylic acid without affecting the amino group. It employed as an intermediate for the synthesis of imidazole derivatives. It plays an essential role to synthesize polysubstituted chiral spirotetrahydropyrans. It is also used in the quantification of pintol after derivatization by gas chromatography/ mass spectrometry.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
1-(Trimethylsilyl)imidazole acts as a silylating agent for alcohols, carbohydrates and 1,3-dicarbonyl compounds. It is a derivatization reagent used for selective silylation of hydroxyl groups and carboxylic acid without affecting the amino group. It employed as an intermediate for the synthesis of imidazole derivatives. It plays an essential role to synthesize polysubstituted chiral spirotetrahydropyrans. It is also used in the quantification of pintol after derivatization by gas chromatography/ mass spectrometry.

Solubility
Miscible with most common organic solvents. It decomposes in water.

Notes
Moisture and light sensitive. Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Incompatible with strong oxidizing agents and strong acids.
WARNING: Reproductive Harm - www.P65Warnings.ca.gov
RUO – Research Use Only

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