Acetamide is used as an industrial solvent, plasticizer, wetting and penetrating agent. It is also used for the transamidation of carboxamides in 1,4-dioxane. It finds application in lacquers and soldering flux. Further, it acts as a precursor to thioacetamide.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Applications
Acetamide is used as an industrial solvent, plasticizer, wetting and penetrating agent. It is also used for the transamidation of carboxamides in 1,4-dioxane. It finds application in lacquers and soldering flux. Further, it acts as a precursor to thioacetamide.
Solubility
Soluble in water.
Notes
Moisture sensitive. Incompatible with strong oxidizing agents, strong acids, strong bases and strong reducing agents.
RUO – Research Use Only
General References:
- Useful additive for brominations of acid-sensitive compounds in non-polar solvents since it forms a stable, insoluble 1:1 complex with HBr: Chem. Ber., 82, 275 (1949).
- For amidocarbonylation in the presence of carbon monoxide and hydrogen in a route to phenylalanine, see Benzyl chloride, A12481.
- D'Amico, F.; Rossi, B.; Camisasca, G.; Bencivenga, F.; Gessini, A.; Principi, E.; Cucini, R.; Masciovecchio, C. Slow-to-fast transition of hydrogen bond dynamics in acetamide hydration shell formation. Phys. Chem. Chem. Phys. 2015, 17 (16), 10987-10992.
- Aguilar-Pineda, J. A.; Méndez-Maldonado, G. A.; Núñez-Rojas, E.; Alejandre, J. Parametrisation of a force field of acetamide for simulations of the liquid phase. Mol. Phys. 2015, 113 (17-18), 2716-2724.