Thermo Scientific Chemicals

Phenyl chloroformate, 99%, Thermo Scientific Chemicals

Catalog number: A12618.22
100 g, Each
Thermo Scientific Chemicals

Phenyl chloroformate, 99%, Thermo Scientific Chemicals

Catalog number: A12618.22
100 g, Each
Quantity
Catalog number: A12618.22
also known as A12618-22
Price (USD)
Quantity
-
Have Questions?

Chemical Identifiers

CAS
1885-14-9
IUPAC Name
phenyl carbonochloridate
Molecular Formula
C7H5ClO2
InChI Key
AHWALFGBDFAJAI-UHFFFAOYSA-N
SMILES
ClC(=O)OC1=CC=CC=C1
Form
Liquid
Assay (GC)
≥98.5% (UK-sourced material)
Assay from Supplier's CofA
≥98.5% (US-sourced material)
Comment
Material sourced in UK and US
Identification (FTIR)
Conforms (UK-sourced material)

Description

Phenyl chloroformate is used in the synthesis of poly(2-(phenoxycarbonyloxy)ethyl methacrylate) and phenyl-(4-vinylphenyl) carbonate. It acts as a precursor of phenyl mixed anhydrides which are used in peptide coupling reactions. It serves as a dehydrating reagent for the conversion of primary amides to nitriles and an intermediate in the synthesis of pharmaceuticals and carbamates.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Phenyl chloroformate is used in the synthesis of poly(2-(phenoxycarbonyloxy)ethyl methacrylate) and phenyl-(4-vinylphenyl) carbonate. It acts as a precursor of phenyl mixed anhydrides which are used in peptide coupling reactions. It serves as a dehydrating reagent for the conversion of primary amides to nitriles and an intermediate in the synthesis of pharmaceuticals and carbamates.

Solubility
Miscible with N,N-dimethylformamide.

Notes
Store in cool place. Moisture sensitive. Keep the container tightly closed in a dry and well-ventilated place. Incompatible with bases, alcohols and amines. Hydrolyses in water.
RUO – Research Use Only

Figures

Documents & Downloads

Certificates

    Frequently asked questions (FAQs)

    Citations & References

    Search citations by name, author, journal title or abstract text