4,4-Dimethyl-2-oxazoline is used in the fictionalization of a non-activated carbon-hydrogen bond.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Applications
4,4-Dimethyl-2-oxazoline is used in the fictionalization of a non-activated carbon-hydrogen bond.
Solubility
Hydrolyzes with water.
Notes
Moisture Sensitive. Store in cool dry place in tightly closed container. With good ventilation. Store away from oxidizing agent.
RUO – Research Use Only
General References:
- Sean H. Wiedemann; Robert G. Bergman; and Jonathan A. Ellman. Rhodium-Catalyzed Direct C-H Addition of 4,4-Dimethyl-2-oxazoline to Alkenes. Org. Lett. 2004, 6(10), 1685-1687.
- G. Balavoine; J.C. Clinet. Cyclopalladated 2-t-butyl-4,4-dimethyl-2-oxazoline: its preparation, and use in the functionalisation of a non-activated carbon-hydrogen bond. Journal of Organometallic Chemistry. 1990, 390(3), c84-c88.
- For reviews of the chemistry of oxazolines, see: Chem. Rev., 71, 483 (1971); Angew. Chem. Int. Ed., 15, 270 (1976); Tetrahedron, 41, 837 (1985); 50, 2297 (1994).