Vitamin of the B complex with hypolipidemic properties occurring in various animal and plant tissues. Required by the body for the formation of coenzymes NAD and NADP.Nicotinic acid is used as an antidyslipidemic agent. It is also used to improve all lipoproteins well above the vitamin requirement and lowers the total cholesterol, bad LDL-cholesterol, and triglyceride levels. Further, it is used as a food additive in food industries, cosmetics and pharmaceuticals. In addition to this, it is used in medication, nutrient, enriched flours and in electroplating baths.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Solubility
Soluble in water. Slightly soluble in ethanol and ethyl ether. Insoluble in most lipid solvents.
Notes
Light sensitive. Store in a cool place. Incompatible with strong oxidizing agents.
RUO – Research Use Only
Cheng, X.; Hookway, E. S.; Kashima, T.; Oppermann, U.; Galione, A.; Athanasou, N. A. The Role of Calcium and Nicotinic Acid Adenine Dinucleotide Phosphate (NAADP) in Human Osteoclast Formation and Resorption. Calcif. Tissue Int. 2015, 96 (1), 73-79.
Trabbic, C. J.; Zhang, F.; Walseth, T. F.; Slama, J. T. Nicotinic Acid Adenine Dinucleotide Phosphate Analogues Substituted on the Nicotinic Acid and Adenine Ribosides. Effects on ReceptorMediated Ca2+ Release. J. Med. Chem. 2015, 58 (8), 3593-3610.