2-Bromo-3-hydroxypyridine is used to produce 2-bromo-4,6-diiodo-3-pyridinol. It is also used in azo dyes and in the synthesis of pterocellin A by reacting with kojic acid and in synthesis of orelline.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Applications
2-Bromo-3-hydroxypyridine is used to produce 2-bromo-4,6-diiodo-3-pyridinol. It is also used in azo dyes and in the synthesis of pterocellin A by reacting with kojic acid and in synthesis of orelline.
Solubility
Soluble in alcohol. Insoluble in water.
Notes
Incompatible with strong oxidizing agents and strong acids.
RUO – Research Use Only
Parhi, A. K.; Xiang, A.; Bauman, J. D.; Patela, D.; Vijayan, R. S. K.; Das, K.; Arnold, E.; LaVoie, E. J. Phenyl substituted 3-hydroxypyridin-2(1H)-ones: Inhibitors of influenza A endonuclease. Bioorg. Med. Chem. 2013, 21 (21), 6435-6446.
Ganguly, N. C.; Mondal, P.; Roy, S.; Mitra, P. Ligand-free copper-catalyzed efficient one-pot access of benzo[b]pyrido[3,2-f][1,4]oxazepinones through O-heteroarylation-Smiles rearrangement-cyclization cascade. RSC Adv. 2014, 4 (98), 55640-55648.
Kato, Y.; Kawasaki, M.; Nigo, T.; Nakamur, S.; Fusano, A.; Teranishi, Y.; Ito, M. N.; Sumiyoshi, T. Identification of 2,3-disubstituted pyridines as potent, orally active PDE4 inhibitors. Bioorg. Med. Chem. 2013, 21 (18), 5851-5854.