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Iodobenzene, 98%, Thermo Scientific Chemicals
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Catalog number A12788.0B
also known as A12788-0B
Price (USD)/ Each
360.65
Online exclusive
400.00 Save 39.35 (10%)
-
Quantity:
1000 g
Price (USD)/ Each
360.65
Online exclusive
400.00 Save 39.35 (10%)
Iodobenzene, 98%, Thermo Scientific Chemicals
Catalog numberA12788.0B
Price (USD)/ Each
360.65
Online exclusive
400.00 Save 39.35 (10%)
-
Chemical Identifiers
CAS591-50-4
Specifications
Specification Sheet
Specification SheetAppearance (Color)Clear colorless to yellow
FormLiquid
Assay (GC)≥97.5%
Identification (FTIR)Conforms
Refractive Index1.6180-1.6220 @ 20?C
Iodobenzene is used to prepare biphenyl and stilbene. It reacts with magnesium to form the Grignard reagent, a phenylmagnesium iodide used in organic synthesis. It finds application as a solid chlorine source by reacting with chlorine to form a complex, iodobenzene dichloride. It serves as a substrate in Sonogashira reaction which is used to form a carbon-carbon bond between a terminal alkyne and an aryl halide.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Applications
Iodobenzene is used to prepare biphenyl and stilbene. It reacts with magnesium to form the Grignard reagent, a phenylmagnesium iodide used in organic synthesis. It finds application as a solid chlorine source by reacting with chlorine to form a complex, iodobenzene dichloride. It serves as a substrate in Sonogashira reaction which is used to form a carbon-carbon bond between a terminal alkyne and an aryl halide.
Solubility
Miscible with ethanol, chloroform and ether. Slightly miscible with dimethyl sulfoxide. Immiscible with water.
Notes
Light sensitive. Incompatible with magnesium and strong oxidizing agents.
Iodobenzene is used to prepare biphenyl and stilbene. It reacts with magnesium to form the Grignard reagent, a phenylmagnesium iodide used in organic synthesis. It finds application as a solid chlorine source by reacting with chlorine to form a complex, iodobenzene dichloride. It serves as a substrate in Sonogashira reaction which is used to form a carbon-carbon bond between a terminal alkyne and an aryl halide.
Solubility
Miscible with ethanol, chloroform and ether. Slightly miscible with dimethyl sulfoxide. Immiscible with water.
Notes
Light sensitive. Incompatible with magnesium and strong oxidizing agents.
RUO – Research Use Only
General References:
- Active methylene compounds undergo CuI-catalyzed phenylation in DMSO: J. Org. Chem., 58, 7606 (1993).
- In the presence of Pd catalysts, couples with a wide range of acrylic species or allylic alcohols in the Heck reaction. For example (2-methyl-2-propen-1-ol), see: Org. Synth. Coll., 7, 361 (1990).
- For an extensive collection of the synthetically-useful reactions of iodoaromatics, see: Synthesis, 923 (1988).
- Alla, S. K.; Kumar, R. K.; Sadhu, P.; Punniyamurthy, T. Iodobenzene Catalyzed C-H Amination of N-Substituted Amidines Using m-Chloroperbenzoic Acid. Org. Lett. 2013, 15 (6), 1334-1337.
- Kurbangalieva, A.; Carmichael, D.; Hii, K. K.; Jutand, A.; Brown, J. M. Oxidative Addition to Palladium (0) Diphosphine Complexes: Observations of Mechanistic Complexity with Iodobenzene as Reactant. Chem. Eur. J. 2014, 20 (4), 1116-1125.