Ethyl methanesulfonate is used as mutagen for both mammalian and plant cells. It finds application as a model alkylating agent in the study of deoxyribonucleic acid (DNA) repair processes.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Applications
Ethyl methanesulfonate is used as mutagen for both mammalian and plant cells. It finds application as a model alkylating agent in the study of deoxyribonucleic acid (DNA) repair processes.
Solubility
Miscible with water.
Notes
Special handling precautions required. View MSDS prior to purchase. MSDS available online at www.alfa.com.Moisture sensitive. Keep the container tightly closed in a dry and well-ventilated place. Incompatible with strong oxidizing agents and strong bases.
RUO – Research Use Only
General References:
- Hartwig, B.; James, G. V.; Konrad, K.; Schneeberger, K.; Turck, F. Fast isogenic mapping-by-sequencing of ethyl methanesulfonate-induced mutant bulks. Plant Physiol. 2012, 160 (2), 591-600.
- Gunther, W. C.; Coffing, S. L.; Dickinson, D. A.; Engel, M. E.; Fiedler, R. D.; O'Lone, S. D.; Dobo, K. L. Evaluation of the Pig-a, micronucleus, and comet assay endpoints in a 28-day study with ethyl methanesulfonate. Environ Mol Mutagen 2014, 55 (6), 492-499.