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2-Hydroxy-4-methoxybenzaldehyde, 98%, Thermo Scientific Chemicals
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Catalog number A12971.06
also known as A12971-06
Price (USD)/ Each
74.70
-
Quantity:
5 g
Price (USD)/ Each
74.70
2-Hydroxy-4-methoxybenzaldehyde, 98%, Thermo Scientific Chemicals
Catalog numberA12971.06
Price (USD)/ Each
74.70
-
Chemical Identifiers
CAS673-22-3
IUPAC Name2-hydroxy-4-methoxybenzaldehyde
Molecular FormulaC8H8O3
InChI KeyWZUODJNEIXSNEU-UHFFFAOYSA-N
SMILESCOC1=CC=C(C=O)C(O)=C1
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Specifications
Specification Sheet
Specification SheetAppearance (Color)Pale cream to pale brown or pale pink
FormCrystals or powder or crystalline powder
Melting Point (clear melt)39.0-46.0?C
Assay (GC)≥97.5%
It is employed in the synthesis of Schiff base ligand. It is applied as a reactant in the synthesis of LPA1R antagonists used in the inhibition of LPA-induced proliferation and contraction of normal human lung fibroblasts. Also used in the synthesis of tyrosine kinase 6 proteinase inhibitors.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Applications
It is employed in the synthesis of Schiff base ligand. It is applied as a reactant in the synthesis of LPA1R antagonists used in the inhibition of LPA-induced proliferation and contraction of normal human lung fibroblasts. Also used in the synthesis of tyrosine kinase 6 proteinase inhibitors.
Solubility
Solubility in methanol is almost transparent. Insoluble in water.
Notes
Air sensitive. Store away from oxidizing agents, bases and air/oxygen. Keep the container tightly closed and place it in a cool, dry and well ventilated condition. Store under inert gas.
It is employed in the synthesis of Schiff base ligand. It is applied as a reactant in the synthesis of LPA1R antagonists used in the inhibition of LPA-induced proliferation and contraction of normal human lung fibroblasts. Also used in the synthesis of tyrosine kinase 6 proteinase inhibitors.
Solubility
Solubility in methanol is almost transparent. Insoluble in water.
Notes
Air sensitive. Store away from oxidizing agents, bases and air/oxygen. Keep the container tightly closed and place it in a cool, dry and well ventilated condition. Store under inert gas.
RUO – Research Use Only
General References:
- Basak S, et al. Synthesis, crystal structures and fluorescence properties of two new di-and polynuclear Cd (II) complexes with N2O donor set of a tridentate Schiff base ligand.Polyhedron.,2008,27(4), 1193-1200.
- Jihua Wang, et al. Antimicrobial and antioxidant activities of the root bark essential oil of Periploca sepium and its main component 2-hydroxy-4-methoxybenzaldehyde.Molecules.,2010,15(8), 5807-5817 .
- I Kubo and I Kinst-Hori. 2-Hydroxy-4-methoxybenzaldehyde: a potent tyrosinase inhibitor from African medicinal plants.lanta Med.,1999,65(1), 19-22.
- Condensation with t-butyl acrylate results in cyclization to t-butyl 7-methoxychromene-3-carboxylate: J. Med. Chem., 36, 3580 (1993):
- With (Ethoxycarbonyl methyl ene) triphenyl phosphorane, A12896, in N,N-diethylaniline cyclization to 7-methoxycoumarin occurs: Heterocycles, 39, 613 (1994).