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Sulfanilamide, 98%, Thermo Scientific Chemicals
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Catalog number A13001.22
also known as A13001-22
Price (USD)/ Each
34.65
Online exclusive
37.80 Save 3.15 (8%)
-
Quantity:
100 g
Price (USD)/ Each
34.65
Online exclusive
37.80 Save 3.15 (8%)
Sulfanilamide, 98%, Thermo Scientific Chemicals
Catalog numberA13001.22
Price (USD)/ Each
34.65
Online exclusive
37.80 Save 3.15 (8%)
-
Chemical Identifiers
CAS63-74-1
IUPAC Name4-aminobenzene-1-sulfonamide
Molecular FormulaC6H8N2O2S
InChI KeyFDDDEECHVMSUSB-UHFFFAOYSA-N
SMILESNC1=CC=C(C=C1)S(N)(=O)=O
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Specifications
Specification Sheet
Specification SheetAppearance (Color)White
FormCrystals or powder or crystalline powder or fused solid
Assay (HPLC)≥97.5%
Identification (FTIR)Conforms
Melting Point (clear melt)162.0-168.0?C
Sulfonamide antibacterial Sulfanilamide is an antibacterial and used in the treatment of vaginal yeast infections. It is a competitive inhibitor of dihydropteroate synthestase to block the synthesis of folic acid. It serves as an intermediate for the preparation of 2,6-disubstituted anilines by electrophilic substitution followed by removal of the sulfonamide blocking group by desulfonation with sulfuric acid.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Applications
Sulfonamide antibacterial Sulfanilamide is an antibacterial and used in the treatment of vaginal yeast infections. It is a competitive inhibitor of dihydropteroate synthestase to block the synthesis of folic acid. It serves as an intermediate for the preparation of 2,6-disubstituted anilines by electrophilic substitution followed by removal of the sulfonamide blocking group by desulfonation with sulfuric acid.
Solubility
Soluble in water, acetone, ethanol, glycerol, propylene glycol and hydrochloric acid. Insoluble in chloroform, ether, benzene and petroleum ether.
Notes
Incompatible with strong oxidizing agents.
Sulfonamide antibacterial Sulfanilamide is an antibacterial and used in the treatment of vaginal yeast infections. It is a competitive inhibitor of dihydropteroate synthestase to block the synthesis of folic acid. It serves as an intermediate for the preparation of 2,6-disubstituted anilines by electrophilic substitution followed by removal of the sulfonamide blocking group by desulfonation with sulfuric acid.
Solubility
Soluble in water, acetone, ethanol, glycerol, propylene glycol and hydrochloric acid. Insoluble in chloroform, ether, benzene and petroleum ether.
Notes
Incompatible with strong oxidizing agents.
RUO – Research Use Only
General References:
- Intermediate for preparation of 2,6-disubstituted anilines, by electrophilic substitution followed by removal of the sulfonamide blocking group by desulfonation with sulfuric acid. See, e.g.: Org. Synth. Coll., 3, 262 (1955).
- Yang, L.; Zhou, S.; Xiao, Y.; Tang, Y.; Xie, T. Sensitive simultaneous determination of three sulfanilamide artificial sweeters by capillary electrophoresis with on-line preconcentration and contactless conductivity detection. Food Chem. 2015, 188, 446-451.
- Bhattacharya, A.; Sharma, M.; Gulati, A.; Joshi, R., Chanda, S. K.; Ahuja, P. S. Histochemical evaluation of catechins in PEG stressed transgenic tea plants using catechin-specific-diazotized sulfanilamide reagent. Biotech. Histochem. 2015, 90 (1), 45-54.