N-Acetyl-D-glucosamine, 98+%

Name: N-Acetyl-D-glucosamine, 98+%
SKU: A13047.22

N-Acetyl-D-glucosamine, CAS # 72-87-7, is the D isomer of the glucose-derived monomer found in structural polysaccharides.

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Catalog number A13047.22

also known as A13047-22

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100 g

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Chemical Identifiers

CAS7512-17-6

IUPAC NameN-[(3R,4R,5S,6R)-2,4,5-trihydroxy-6-(hydroxymethyl)oxan-3-yl]acetamide

Molecular FormulaC8H15NO6

InChI KeyOVRNDRQMDRJTHS-WZWLWIOANA-N

SMILESCC(=O)N[C@H]1C(O)O[C@H](CO)[C@@H](O)[C@@H]1O

Specifications

Specification Sheet

Appearance (Color)White to pale cream or pale yellow

FormCrystals or powder or crystalline powder

Assay from Supplier's CofA≥98.0% (HPLC)

CommentMaterial Sourced in UK and US

Identification (FTIR)Conforms (UK Sourced Material)

N-Acetyl-D-glucosamine is used in the identification and characterization of N-acetyl-beta-D-hexoaminidase. It is also used in the treatment of osteoarthritis and inflammatory bowel disease (IBD), including ulcerative colitis and Crohn's disease. Further, it is used as a substrate in sialic acid production, cosmetics and in drug development research.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

General Description

• N-Acetyl-D-glucosamine is the acetylated form of glucosamine, a glucose derivative

• It has a role as a prokaryotic metabolism and monomer used in chitin, hyaluronic acid, and polymers within the cell wall

Application

• N-Acetyl-D-Glucosamine can be used for molecular binding studies; research has shown that it attaches to certain microbes and their pathogens

• It is useful for biochemical characterization studies of related glucosamines

RUO – Research Use Only

General References:

Schwein PA, Woo CM. The O-GlcNAc Modification on Kinases. ACS Chem Biol. 2020 Mar 20;15(3):602-617. doi: 10.1021/acschembio.9b01015. Epub 2020 Mar 10. PMID: 32155042; PMCID: PMC7253032.
Gorelik A, Illes K, Nagar B. Crystal Structure of the Mannose-6-Phosphate Uncovering Enzyme. Structure. 2020 Apr 7;28(4):426-436.e3. doi: 10.1016/j.str.2020.02.001. Epub 2020 Feb 27. PMID: 32109365.